How to use · The Masterpiece Collection

Two routines.
Two minutes each.

Use the system AM and PM. Dr. Truesdale's order matters — apply thinnest to thickest, water-based before oil-based.

Radiance CleanserStep 1 1
Cleanse

Radiance Cleanser

Amount
½ pump
Wait
—

Massage 30 seconds. Rinse with lukewarm water.

Antioxidant Defense SerumStep 2 2
Defend

Antioxidant Serum

Amount
A few drops
Wait
60 seconds

Press onto face and neck. Wait until tacky before the next step.

Renewal Repair CreamStep 3 3
Repair

Renewal Repair Cream

Amount
1 pump
Wait
—

Layer over serum. Includes the eye area.

4
Protect

Your favorite SPF 30+

Amount
2 fingers
Wait
—

Never skip. We recommend a tinted mineral SPF.

Radiance CleanserStep 1 1
Cleanse

Radiance Cleanser

Amount
½ pump
Wait
—

Remove the day's impurities. Massage 30 seconds, rinse lukewarm.

Age Reversal CreamStep 2 2
Reverse

Age Reversal Cream

Amount
Pea-size
Wait
60 seconds

Start 2–3 nights a week. Build up to every night. Mild tingling is normal.

Renewal Repair CreamStep 3 3
Repair

Renewal Repair Cream

Amount
1 pump
Wait
—

Apply last, over Age Reversal Cream, to finish your evening routine.

Dr. Truesdale's tip

Apply to slightly damp skin. Hydration improves active penetration.

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Why our retinol is different
0.5% encapsulated retinol — releases gradually so it's gentler on deeper skin tones prone to post-inflammatory hyperpigmentation.
Designed and tested with melanin-rich skin first. See real customer results →

The Masterpiece Collection

Our comprehensive AM/PM routine for total skin transformation.

View full guide →

Masterpiece Collection FAQ

The Masterpiece Collection is formulated for all skin types, including sensitive skin. We recommend a patch test before first use.
Many users notice improvements in skin texture and radiance within 2–4 weeks. Optimal anti-aging results are typically seen after 8–12 weeks of consistent use.

Brightening Boost is an evening step, and it goes on after your retinol or anti-aging cream — not before.

With the Masterpiece Collection — PM: Radiance Cleanser → Age Reversal Cream → Brightening Boost Cream → Renewal Repair Cream. Your morning routine stays exactly as shown above, without Brightening Boost. New to retinol, or does your skin run sensitive? Start Age Reversal Cream 2–3 nights a week and use Brightening Boost Cream on the other nights. As your skin adjusts, build up to using both every night: Age Reversal Cream, then Brightening Boost Cream, then Renewal Repair Cream.

With the Brightening Collection — PM: Radiance Cleanser → Brightening Boost Cream → Renewal Repair Cream.

With non-Artisa products — two rules. First, keep Brightening Boost at night, applied after any retinol or anti-aging treatment. Second, don't use it in the same routine as a Vitamin C serum or an exfoliating acid (AHA/BHA) — those belong in your morning routine. Layering Brightening Boost straight over Vitamin C or an acid can cause it to pill and roll off instead of absorbing. Give each layer about 60 seconds to absorb before the next.

Yes — the Masterpiece Collection complements most routines. We recommend using our products as the core of your regimen for the best results.
For optimal results, we recommend the full collection. Each product is also effective on its own and can be incorporated individually.
Yes. Use it at night only. New to retinol? Start 2–3 nights a week, then build up to every night as your skin adjusts. Already using a retinol? You can use it every night. Mild tingling is normal.
Our creams and serums can be applied to the under-eye area gently with your ring finger. Avoid direct contact with the eyes. For retinol, use caution around the delicate eye area.
A broad-spectrum SPF 30 or higher, especially when using actives like vitamin C and retinol.
If you are pregnant or breastfeeding, consult your healthcare provider before use. Avoid retinol-containing products (Age Reversal Cream) during pregnancy.
Store products in a cool, dry place away from direct sunlight. Keep lids closed tightly between uses to maintain efficacy.
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How to use · The Brightening Collection

The Brightening Collection routine.

A targeted 4-product system for dark spots, melasma, and uneven tone — formulated for melanin-rich skin where hyperpigmentation is most common.

Radiance Cleanser1
Cleanse

Radiance Cleanser

Massage 30 seconds. Rinse with lukewarm water.

Antioxidant Defense Serum2
Defend

Antioxidant Serum

A few drops pressed onto face and neck. Wait 60 seconds.

Renewal Repair Cream3
Repair

Renewal Repair Cream

Layer over serum. Includes the eye area.

4
Protect

Your favorite SPF 30+

Non-negotiable with brightening actives. A tinted mineral SPF works beautifully on melanin-rich skin.

Radiance Cleanser1
Cleanse

Radiance Cleanser

Remove the day. Pat dry — leave skin slightly damp.

Brightening Boost Cream2
Correct

Brightening Boost Cream

Apply to clean skin so the brightening complex works overnight.

Renewal Repair Cream3
Repair

Renewal Repair Cream

Seal everything in. Includes the eye area.

The Brightening Collection

Targeted brightening for luminous, even-toned skin.

View full guide →

Brightening Collection FAQ

Anyone targeting dark spots, post-acne marks, melasma, or overall uneven tone. It was formulated for melanin-rich skin first, so it brightens without the irritation that can trigger new hyperpigmentation.
Yes. Brightening Boost Cream is a PM-only step, so your morning routine stays the same. In the evening, apply it after Age Reversal Cream and finish with Renewal Repair Cream. New to retinol, or does your skin run sensitive? Start Age Reversal Cream 2–3 nights a week and use Brightening Boost Cream on the other nights. As your skin adjusts, build up to using both every night: Age Reversal Cream, then Brightening Boost Cream, then Renewal Repair Cream.
Most customers report first changes in tone around 4 weeks, with more even, luminous skin by 8–12 weeks of consistent AM/PM use.
Sun exposure is what created the dark spots. Daily SPF 30+ protects your progress — skipping it undoes the brightening work.
Shop the Brightening Collection — $199 every 2 months →
“My face tone has evened out beautifully, skin is butter soft, and fine lines have softened.”
Jacqueline S. · ✓ Verified · Masterpiece Collection
Ready to start your routine?

The Masterpiece Collection

The complete 4-step anti-aging system — firming, texture, and overall renewal.

$199 on subscription · $229 one-time
Save $195 vs buying individually

The Brightening Collection

The targeted 4-step system for dark spots, melasma, and uneven tone.

$199 on subscription · $229 one-time
Save $185 vs buying individually