Shop · Step 2 · Defend · Antioxidant Defense Serum

AM Only

Dr. Carl Truesdale, MD

Double Board-Certified Facial Plastic Surgeon · Beverly Hills

Formulated by Founder

Step 2 · Antioxidant Defense · Morning

Antioxidant Defense Serum

Name: Antioxidant Defense Serum
Brand: Artisa Skincare
SKU: ART-SRM-ANT-1OZ
Price: 122.00 USD
Availability: InStock
Rating: 4.5 (4 reviews)

Dual-form Vitamin C, niacinamide, ferulic acid, CoQ10 · 30 mL / 1 fl oz

★★★★★ 4.5 · 4 verified reviews

Your daily Vitamin C, ferulic acid, and radiance shield. Dual-form Vitamin C, niacinamide, ferulic acid, and CoQ10 protect against environmental aging and brighten tone — the morning step that sets everything else up.

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Antioxidant Serum — defend, repair & brighten The real reason your vitamin C isn’t working More from Dr. Truesdale on YouTube →

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Tested on all skin tones

Including melanin-rich types

4.5 ★★★★★

4 verified reviews

Every review is from a confirmed purchase

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Set your expectations

What to expect, and when

Real skin change follows your skin’s own renewal cycle. Here is the honest timeline.

Weeks 1–2

Skin feels more hydrated, calm and comfortable. Surface texture starts to smooth.

Weeks 3–4

Tone looks brighter and more even; makeup sits better.

Weeks 8–12

Firmness and fine lines improve. This is the point worth judging results on.

Individual results vary. Backed by our 30-day money-back guarantee — if it is not working for you, we will refund the product.

★

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Active Ingredients

The science inside Antioxidant Defense Serum.

Click any ingredient to see exactly how it works and why Dr. Truesdale chose it.

Tetrahexyldecyl Ascorbate (Oil-Soluble Vit C)

AM Only · Deep brightening

Most stable, penetrating form of Vitamin C

Unlike standard L-ascorbic acid, THDA doesn't oxidize, works without low pH, and penetrates the lipid layer to work where brightening and collagen synthesis actually happen. Ideal for melanin-rich skin.

BrighteningStable Vitamin CDeep penetrationMelanin-safe

Sodium Ascorbyl Phosphate (Water-Soluble Vit C)

AM Only · Surface brightening

Second form of Vitamin C — surface brightening and protection

While THDA works deep, SAP brightens at the skin surface. Together the dual-form Vitamin C delivers brightening at both levels — far more complete than single-form serums.

Surface brighteningStableTwo-level approach

Niacinamide 4%

AM Only · Tone + barrier

One of the most well-researched actives in skincare

At the evidence-backed 4% concentration, niacinamide inhibits melanin transfer, reduces redness, minimizes pores, and strengthens barrier. Particularly valuable for melanin-rich skin.

Pore minimizingRedness reductionHyperpigmentationBarrier support

Ferulic Acid

AM Only · Antioxidant amplifier

Doubles the photoprotection of Vitamin C

The vitamin C + E + ferulic pairing is the most-proven antioxidant combination in skincare. Artisa includes it for exactly that reason — it stabilizes Vitamin C and doubles its UV protection efficacy throughout the day.

AntioxidantVitamin C amplifierUV defense

How To Use

Your routine

☀ Morning

Apply 3–5 drops to clean, dry skin every morning. Gently press into skin. Allow to absorb for 60 seconds before applying Renewal Repair Cream and SPF. Vitamin C + SPF together outperform either alone.

🌙 Evening

Not applicable — this is a morning-only serum. In the evening, use Radiance Cleanser → Renewal Repair Cream → Age Reversal Cream.

Quick answers

Yes — specifically designed for it. Every formula is tested across all skin tones in Dr. Truesdale's Beverly Hills practice.

Give it a real try — if it hasn't worked for you, email us within 30 days of delivery and we'll refund the cost of the product. No return needed, no problem.

Yes. Antioxidant Defense Serum is AM-only and pairs perfectly with Age Reversal Cream (PM retinol). The Masterpiece Collection is built around exactly this layering.

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