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AM Only Antioxidant Defense Serum
Antioxidant Defense Serum
Antioxidant Defense Serum
Antioxidant Defense Serum
Antioxidant Defense Serum
Antioxidant Defense Serum
CT
Dr. Carl Truesdale, MD
Double Board-Certified Facial Plastic Surgeon · Beverly Hills
Formulated by Founder
Step 2 · Antioxidant Defense · Morning

Antioxidant Defense Serum

Dual-form Vitamin C, niacinamide, ferulic acid, CoQ10 · 30ML
★★★★★ 4.8 · verified reviews ✓ Judge.me Verified

Your daily Vitamin C, ferulic acid, and radiance shield. Dual-form Vitamin C, niacinamide, ferulic acid, and CoQ10 protect against environmental aging and brighten tone — the morning step that sets everything else up.

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Tested on all skin tones
Including melanin-rich types
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Active Ingredients

The science inside Antioxidant Defense Serum.

Click any ingredient to see exactly how it works and why Dr. Truesdale chose it.

Tetrahexyldecyl Ascorbate (Oil-Soluble Vit C)
AM Only · Deep brightening
+
Most stable, penetrating form of Vitamin C
Unlike standard L-ascorbic acid, THDA doesn't oxidize, works without low pH, and penetrates the lipid layer to work where brightening and collagen synthesis actually happen. Ideal for melanin-rich skin.
BrighteningStable Vitamin CDeep penetrationMelanin-safe
Sodium Ascorbyl Phosphate (Water-Soluble Vit C)
AM Only · Surface brightening
+
Second form of Vitamin C — surface brightening and protection
While THDA works deep, SAP brightens at the skin surface. Together the dual-form Vitamin C delivers brightening at both levels — far more complete than single-form serums.
Surface brighteningStableTwo-level approach
Niacinamide 4%
AM Only · Tone + barrier
+
One of the most clinically proven actives in skincare
At the evidence-backed 4% concentration, niacinamide inhibits melanin transfer, reduces redness, minimizes pores, and strengthens barrier. Particularly valuable for melanin-rich skin.
Pore minimizingRedness reductionHyperpigmentationBarrier support
Ferulic Acid
AM Only · Antioxidant amplifier
+
Doubles the photoprotection of Vitamin C
Why SkinCeuticals C E Ferulic is the gold standard serum. Artisa includes it for the same reason — it stabilizes Vitamin C and doubles its UV protection efficacy throughout the day.
AntioxidantVitamin C amplifierUV defense
How To Use

Your routine

☀ Morning

Apply 3–5 drops to clean, dry skin every morning. Gently press into skin. Allow to absorb for 60 seconds before applying Renewal Repair Cream and SPF. Vitamin C + SPF together outperform either alone.

🌙 Evening

Not applicable — this is a morning-only serum. In the evening, use Radiance Cleanser → Renewal Repair Cream → Age Reversal Cream.

Verified Reviews

What customers say.

4.8
★★★★★
Judge.me verified
★★★★★

"My skin has looked so much more even and bright since I started using this every morning. The Vitamin C difference is real."

Simone R.
Age 38 · Brightening focus
✓ Verified
★★★★★

"I've tried expensive Vitamin C serums before. This one actually does what it promises — especially paired with the cleanser."

Marcus T.
Age 45 · AM routine · Deeper skin tone
✓ Verified
★★★★★

"Absorbs beautifully. No staining, no stickiness. Skin looks genuinely healthier after a month."

Claire M.
Texture + radiance
✓ Verified
Quick answers
Yes — specifically designed for it. Every formula is tested across all skin tones in Dr. Truesdale's Beverly Hills practice.
If you're not satisfied for any reason within 30 days, we'll refund every dollar — no forms, no hoops.
Yes. Antioxidant Defense Serum is AM-only and pairs perfectly with Age Reversal Cream (PM retinol). The Masterpiece Collection is built around exactly this layering.
Complete Your Routine

Also from Artisa

Build a complete routine with the Masterpiece or Brightening Collection for the best results.

Antioxidant Defense Serum ★★★★★ · reviews · Free U.S. shipping over $75
$103
$122